ANTI-SELECTIVE ASYMMETRIC ALDOL REACTIONS - ENANTIOSELECTIVE SYNTHESIS OF ANTI-ALPHA,BETA-DIHYDROXY PHENYL ESTER DERIVATIVES

被引：21

作者：

KOBAYASHI, S

KAWASUJI, T

机构：

[1] Department of Applied Chemistry, Faculty of Science, Science University of Tokyo (SUT), Shinjuku-ku, Tokyo, 162, Kagurazaka

来源：

TETRAHEDRON LETTERS | 1994年 / 35卷 / 20期

关键词：

D O I：

10.1016/S0040-4039(00)76899-7

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

In the presence of a chiral tin(II) Lewis acid, the silyl enol ether derived from (E)-phenyl alpha-t-butyldimethylsiloxyacetate reacted with aldehydes to afford the corresponding anti-aldol adducts, anti-alpha,beta-dihydroxy ester derivatives, in high yields with high diastereo- and enantioselectivities.

引用

页码：3329 / 3332

页数：4

共 8 条

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