URTICARIAL VASCULITIS ASSOCIATED WITH A MONOCLONAL IGM GAMMOPATHY - SCHNITZLERS SYNDROME

被引：43

作者：

BORRADORI, L

RYBOJAD, M

PUISSANT, A

DALLOT, A

VEROLA, O

MOREL, P

机构：

[1] HOP ST LOUIS, DERMATOL CLIN, 1 AVE CLAUDE VELLEFAUX, F-75475 PARIS 10, FRANCE

[2] HOP ST LOUIS, CENT PATHOL LAB, F-75475 PARIS 10, FRANCE

来源：

BRITISH JOURNAL OF DERMATOLOGY | 1990年 / 123卷 / 01期

关键词：

D O I：

10.1111/j.1365-2133.1990.tb01831.x

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

We describe two cases of Schnitzler's syndrome presenting with urticarial vasculitis, in which there was a monoclonal IgM of kappa light-chain isotype. Skin histology showed a perivascular leucocytic infiltrate and leucocytoclasis. One patient had an abnormal complement profile and positive rheumatoid factor while the other had antibodies to unidentified soluble nuclear antigens, anti-cytoplasmic antibodies and circulating immune complexes. In addition, in the first case deposits of IgM, C3 and, to a lesser degree, of IgG were observed in the walls of small blood vessels.

引用

页码：113 / 118

页数：6