THE CHANGING-ROLE OF SURGERY IN METASTATIC NONSEMINOMATOUS GERM-CELL TUMOR

被引：13

作者：

CASSIDY, J ^{[1
]}

LEWIS, CR ^{[1
]}

KAYE, SB ^{[1
]}

KIRK, D ^{[1
]}

机构：

[1] WESTERN INFIRM & ASSOCIATED HOSP,CANC RES CAMPAIGN,DEPT UROL,GLASGOW G11 6NT,SCOTLAND

来源：

BRITISH JOURNAL OF CANCER | 1992年 / 65卷 / 01期

关键词：

D O I：

10.1038/bjc.1992.24

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

In the last 2 years (1989-1990) we have treated a total of 53 patients with metastatic nonseminomatous germ cell tumours (teratoma). In ten cases surgery to remove residual abdominal masses was required on completion of chemotherapy and normalisation of tumour markers (HCG and AFP). In a further three patients with large intra-abdominal masses and little or no other sites of disease surgery was performed as a therapeutic intervention, in the context of plateauing or rising tumour markers despite intensive chemotherapy. In all three, this approach resulted in a rapid fall in tumour markers, and following further chemotherapy all three remain disease free at 7, 12 and 25 months. For this small sub-group of patient failing to respond to chemotherapy who have resectable lesions, interventional surgery should be considered as part of a combined approach to treatment.

引用

页码：127 / 129

页数：3