FAILURE OF SURGERY AND ISOTRETINOIN TO RELIEVE JAW IMMOBILIZATION IN FIBRODYSPLASIA OSSIFICANS PROGRESSIVA - REPORT OF 2 CASES

被引：25

作者：

CROFFORD, LJ

BRAHIM, JS

ZASLOFF, MA

MARINI, JC

机构：

[1] NIAMSD,ARTHRITIS & RHEUMAT BRANCH,CONNECT TISSUE SECT,BETHESDA,MD

[2] NIDR,CLIN INVEST & PATIENT CARE BRANCH,BETHESDA,MD

[3] HOSP UNIV PENN,DEPT PEDIAT,DIV HUMAN GENET,PHILADELPHIA,PA 19104

[4] NICHHD,HUMANG GENET BRANCH,CONNECT TISSUE DISORDERS UNIT,BETHESDA,MD

来源：

JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY | 1990年 / 48卷 / 02期

关键词：

D O I：

10.1016/S0278-2391(10)80212-5

中图分类号：

R78 [口腔科学];

学科分类号：

1003 ;

摘要：

Two patients with fibrodyplasia ossificans progressiva who presented with jaw immobilization due to formation of bone between the maxilla and mandible were treated with surgical resection of their ectopic bone in conjunction with experimental, adjunctive medical therapy using isotretinoin. Both patients had recurrence of their ectopic ossification within 2 months of surgery. Surgery to remove joint-bridging ossifications in FOP is not recommended. © 1990, American Association of Oral and Maxillofacial Surgeons. All rights reserved.. All rights reserved.

引用

页码：204 / 208

页数：5

共 14 条

[1] MODULATION OF THE RABBIT CHONDROCYTE PHENOTYPE BY RETINOIC ACID TERMINATES TYPE-II COLLAGEN-SYNTHESIS WITHOUT INDUCING TYPE-I COLLAGEN - THE MODULATED PHENOTYPE DIFFERS FROM THAT PRODUCED BY SUBCULTURE [J].