IMMUNOLOGICAL ASSESSMENT OF EXPOSURE TO ECHINOCOCCUS-GRANULOSUS IN A RURAL DOG-POPULATION IN URUGUAY

被引：15

作者：

GASSER, RB

PARADA, L

ACUNA, A

BURGES, C

LAURENSON, MK

GULLAND, FMD

REICHEL, MP

PAOLILLO, E

机构：

[1] FDN SAN ANTONIO PADUA,ECHINOCOCCOSIS GRP,DURAZNO,URUGUAY

[2] GAME CONSERVANCY,GUNNERSIDE,N YORKSHIRE,ENGLAND

[3] UNIV LONDON,INST ZOOL,LONDON,ENGLAND

来源：

ACTA TROPICA | 1994年 / 58卷 / 3-4期

基金：

澳大利亚研究理事会;

关键词：

EPIDEMIOLOGY; ECHINOCOCCOSIS; DOG; DIAGNOSIS; URUGUAY;

D O I：

10.1016/0001-706X(94)90012-4

中图分类号：

R38 [医学寄生虫学]; Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ; 100103 ;

摘要：

An ELISA was used to screen a dog population in Uruguay (Sarandi Del Yi, Durazno District) for the prevalence of specific serum antibodies (IgG, IgA and IgE) to Echinococcus granulosus. The sensitivity (61%) and specificity (97%) of the ELISA were determined using well-defined serum groups. A total of 408 dogs from Sarandi del Yi and environs were screened serologically, and 29.7% (8.6-13.8% for each antibody class) of dogs had positive levels of antibody to E. granulosus. This antibody prevalence (exposure) was significantly higher than the percentage of dogs found to be positive for E. granulosus worms by arecoline purgation (7.6%). This level of exposure to E. granulosus determined by ELISA is considered unacceptable from a public health perspective. Measures will now focus on obtaining data on the true prevalence of current infection in this dog population and on determining the transmission patterns of the disease in this endemic region.

引用

页码：179 / 185

页数：7

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