CLONING AND SEQUENCING OF CDNA-ENCODING MOUSE GTP CYCLOHYDROLASE-I

被引：54

作者：

NOMURA, T

ICHINOSE, H

SUMIICHINOSE, C

NOMURA, H

HAGINO, Y

FUJITA, K

NAGATSU, T

机构：

[1] FUJITA HLTH UNIV,SCH MED,INST COMPREHENS MED SCI,TOYOAKE,AICHI 47011,JAPAN

[2] FUJITA HLTH UNIV,SCH MED,DEPT PHARMACOL,TOYOAKE,AICHI 47011,JAPAN

来源：

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS | 1993年 / 191卷 / 02期

关键词：

D O I：

10.1006/bbrc.1993.1249

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

A full-length cDNA clone for GTP cyclohydrolase I (EC 3.5.4.16) was isolated from a mouse brain cDNA library by plaque hybridization. The nucleotide sequence determination revealed that the length of the cDNA insert was 994 base pairs. The coding region encoded a protein of 241 amino acid residues with a calculated molecular mass of 27,014 daltons. The deduced amino acid sequence of mouse GTP cyclohydrolase I was found to be highly homologous to rat (96%) and human type 1(89%) enzymes. © 1993 Academic Press.

引用

页码：523 / 527

页数：5

共 24 条

[1] PROTEIN SERINE THREONINE KINASES [J].