CLONING AND SEQUENCING OF CDNA-ENCODING MOUSE GTP CYCLOHYDROLASE-I

被引：54

作者：

NOMURA, T

ICHINOSE, H

SUMIICHINOSE, C

NOMURA, H

HAGINO, Y

FUJITA, K

NAGATSU, T

机构：

[1] FUJITA HLTH UNIV,SCH MED,INST COMPREHENS MED SCI,TOYOAKE,AICHI 47011,JAPAN

[2] FUJITA HLTH UNIV,SCH MED,DEPT PHARMACOL,TOYOAKE,AICHI 47011,JAPAN

来源：

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS | 1993年 / 191卷 / 02期

关键词：

D O I：

10.1006/bbrc.1993.1249

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

A full-length cDNA clone for GTP cyclohydrolase I (EC 3.5.4.16) was isolated from a mouse brain cDNA library by plaque hybridization. The nucleotide sequence determination revealed that the length of the cDNA insert was 994 base pairs. The coding region encoded a protein of 241 amino acid residues with a calculated molecular mass of 27,014 daltons. The deduced amino acid sequence of mouse GTP cyclohydrolase I was found to be highly homologous to rat (96%) and human type 1(89%) enzymes. © 1993 Academic Press.

引用

页码：523 / 527

页数：5

共 24 条

[21] MULTIPLE MESSENGER-RNA FORMS OF HUMAN GTP CYCLOHYDROLASE-I [J].

TOGARI, A ;

ICHINOSE, H ;

MATSUMOTO, S ;

FUJITA, K ;

NAGATSU, T .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1992, 187 (01) :359-365

[22] CFS HYDROXYLASE COFACTOR LEVELS IN SOME NEUROLOGICAL DISEASES [J].

WILLIAMS, AC ;

LEVINE, RA ;

CHASE, TN ;

LOVENBERG, W ;

CALNE, DB .

JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, 1980, 43 (08) :735-738

[23] SUBSTRATE-SPECIFICITY OF PROTEIN-KINASE-C - USE OF SYNTHETIC PEPTIDES CORRESPONDING TO PHYSIOLOGICAL SITES AS PROBES FOR SUBSTRATE RECOGNITION REQUIREMENTS [J].

WOODGETT, JR ;

GOULD, KL ;

HUNTER, T .

EUROPEAN JOURNAL OF BIOCHEMISTRY, 1986, 161 (01) :177-184

[24]

ZIEGLER I, 1985, J CELL BIOCHEM, V28, P197, DOI 10.1002/jcb.240280303

← 1 2 3 →