THE CONFORMATION OF THE MONOMETHYL ETHERS OF METHYL BETA-LACTOSIDE IN D2O AND ME2SO-D6 SOLUTIONS

被引：15

作者：

FERNANDEZ, P

JIMENEZBARBERO, J

机构：

[1] Grupo de Carbohidratos, Instituto de Química Orgánica General, 28006 Madrid

来源：

CARBOHYDRATE RESEARCH | 1993年 / 248卷

关键词：

D O I：

10.1016/0008-6215(93)84113-K

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The solution conformations of all the possible monomethyl ethers of methyl beta-lactoside have been analysed using molecular mechanics and dynamics calculations and nuclear magnetic resonance data (variable temperature and NOE experiments). The overall shape of all the compounds studied is fairly similar and may be described by conformers included in a low-energy region with PHI = -100 +/- 40-degrees and PSI = -135 +/- 35-degrees, which is ca. 5% of the total potential energy surface for the glycosidic linkages of the disaccharides.

引用

页码：15 / 36

页数：22

共 52 条

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