BELAMCANDAQUINONE-A AND BELAMCANDAQUINONE-B, NOVEL DIMERIC 1,4-BENZOQUINONE DERIVATIVES POSSESSING CYCLOOXYGENASE INHIBITORY ACTIVITY

被引：15

作者：

FUKUYAMA, Y

KIRIYAMA, Y

OKINO, J

KODAMA, M

机构：

[1] Faculty of Pharmaceutical Sciences, Tokushima Bunri University, Tokushima, 770, Yamashiro-cho

来源：

TETRAHEDRON LETTERS | 1993年 / 34卷 / 47期

关键词：

D O I：

10.1016/S0040-4039(00)60419-7

中图分类号：

O62 [有机化学];

学科分类号：

070303 [有机化学]; 081704 [应用化学];

摘要：

Belamcandaquinone A (1), a new dimeric 1,4-benzoquinone derivative, has been isolated as specific cyclooxygenase inhibitor (IC50 8.33 muM) from the seed of Belamcanda chinensis together with belamcandaquinone B (2), an inactive congener, and their structures elucidated on the basis of spectroscopic data and chemical degradation.

引用

页码：7633 / 7636

页数：4

共 6 条

[1]

De Haan J.W, 1973, MAGN RESON CHEM, V5, P147, DOI [10.1002/mrc.1270050309, DOI 10.1002/MRC.1270050309]

[2]

STRUCTURE OF MAGNOLIANIN, A NOVEL TRILIGNAN POSSESSING POTENT 5-LIPOXYGENASE INHIBITORY ACTIVITY [J].