PHOSPHOLIPID DISTRIBUTIONS AND FATTY-ACID COMPOSITION OF LYSOPHOSPHATIDYLCHOLINE AND PHOSPHATIDYLCHOLINE IN RABBIT AQUEOUS-HUMOR, LENS AND VITREOUS

被引：21

作者：

KIM, JO ^{[1
]}

COTLIER, E ^{[1
]}

机构：

[1] UNIV ILLINOIS, MED CTR, DEPT OPHTHALMOL, BIOCHEM LABS, CHICAGO, IL 60680 USA

来源：

EXPERIMENTAL EYE RESEARCH | 1976年 / 22卷 / 06期

关键词：

D O I：

10.1016/0014-4835(76)90001-4

中图分类号：

R77 [眼科学];

学科分类号：

100212 ;

摘要：

The phospholipid distributions in rabbit lens and vitreous humor were remarkably similar to those of rabbit erytnrocytes with a predominance of phosphatidylethanolamine (PE) and phosphatidylcholine (PC) and lesser levels of sphingomyelin. A blood-aqueous and blood vitreous barrier existed for phospholipids. In aqueous humor and vitreous humor, phospholipid concentrations were 1/2-1/30 those in serum. Only PE occurred in higher levels in vitreous than in serum, probably reflecting direct diffusion from the retina. Levels of lysophosphatidlycholine (LPC) in rabbit aqueous humor averaged 4.3 .mu.g/ml. No LPC was present in rabbit lens. The fatty acid composition of PC and LPC was determined in lens, intraocular fluids and serum. PC from rabbit ocular fluids or lens contained a higher proportion of saturated fatty acids than rabbit serum, and the long chain saturated fatty acids (> 22:0) were found only in the ocular fluids.

引用

页码：569 / 576

页数：8