NMR-STUDIES OF DRUGS - METHAQUALONE - APPROACHES TO RIGOROUS H-1 AND C-13 ASSIGNMENTS WITH APPLICATIONS OF ACHIRAL AND CHIRAL SHIFT-REAGENTS

The 1H and 13C NMR spectra of methaqualone 1, have been extensively studied using one and two-dimensional techniques. These 300 MHz 1H and 75 MHz 13C studies have allowed rigorous assignments to be made for the methyl groups and the quinazolinone nucleus. The 60 MHz 1H spectra for 1 in CDCl3 have been examined with. © 1990, Taylor & Francis Group, LLC. All rights reserved.