EFFECTS OF ATSUMI-KABU (RED TURNIP, BRASSICA-CAMPESTRIS L) ANTHOCYANIN ON SERUM-CHOLESTEROL LEVELS IN CHOLESTEROL-FED RATS

Major anthocyanins of root peels of atsumi-kabu (red turnip, Brassica campestris L.) were isolated and identified as cyanidin-3-diglucoside-5-monoglucoside (I, rubrobrassicin), cyanidin-3,5diglucoside (II), and cyanidin-3-monoglucoside (III). The effects of these anthocyanins on serum cholesterol levels were examined in rats fed for 3 weeks on either a control diet based on lardcholesterol or experimental diets containing 0.03%I or 0.045%of a mixture of II and III (I for experiment 1, and mixture of II and III for experiment 2). Significant increases in serum high density lipoprotein (HDL)-cholesterol levels and significant decreases in the atherogenic index ((total cholesterol-HDL-cholesterol)/HDL-cholesterol) were observed in rats fed on a diet containing I (experiment 1). In experiment 1, total cholesterol- HDL-cholesterol (VLDL- + LDL-cholesterol) somewhat decreased in rats fed on a diet containing I. A significant decrease in atherogenic index was observed in rats fed on a diet containing the mixture of II and III (experiment 2). Besides, in experiment 2, total cholesterol and total cholesterol- HDL-cholesterol somewhat decreased in rats fed on a diet containing the mixture of II and III. © 1990 by the Japan Society for Bioscience, Biotechnology, and Agrochemistry. All rights reserved.