UNRESECTABLE HEPATOCELLULAR-CARCINOMA - ANALYSIS OF PROGNOSTIC FACTORS IN TRANSCATHETER MANAGEMENT

被引：86

作者：

HATANAKA, Y

YAMASHITA, Y

TAKAHASHI, M

KOGA, Y

SAITO, R

NAKASHIMA, K

URATA, J

MIYAO, M

机构：

[1] Department of Radiology, Kumamoto University, School of Medicine, Kumamoto 860

来源：

RADIOLOGY | 1995年 / 195卷 / 03期

关键词：

ARTERIES; THERAPEUTIC BLOCKADE; CHEMOTHERAPEUTIC INFUSION; LIVER NEOPLASMS;

D O I：

10.1148/radiology.195.3.7754005

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

PURPOSE: To evaluate the effect of transcatheter management of hepatocellular carcinoma (HCC) on survival. MATERIALS AND METHODS: A prospective trial of transcatheter arterial embolization (TAE) was performed in patients with unresectable HCC. Three hundred twenty-two patients (265 men, 57 women; age range, 30-83 years) underwent TAE alone: 60 patients underwent TAE with gelatin sponge (GS) that contained anticancer agents (protocol 1); 78, TAE with GS and iodized oil mixed with anticancer agents (protocol 2); and 159, TAE with iodized oil with anticancer agents (protocol 3). A Cox proportional hazard model was used to analyze prognostic factors. RESULTS: In the randomized group (n = 272), survival rates for protocols 1, 2, and 3 were 80.4%, 86.3%, and 65.9%, respectively, at 1 year. Findings of analysis of prognostic factors showed that extrahepatic metastases, ascites, tumor extension, and icterus were the important factors. CONCLUSION: TAE with GS was superior to TAE without GS. Patient characteristics were important factors for survival.

引用

页码：747 / 752

页数：6

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