MOLECULAR-GENETICS OF POLYAMINE SYNTHESIS IN EUKARYOTIC CELLS

被引：533

作者：

HEBY, O ^{[1
]}

PERSSON, L ^{[1
]}

机构：

[1] UNIV LUND,DEPT PHYSIOL,S-22362 LUND,SWEDEN

来源：

TRENDS IN BIOCHEMICAL SCIENCES | 1990年 / 15卷 / 04期

关键词：

D O I：

10.1016/0968-0004(90)90216-X

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The polyamines putrescine, spermidine and spermine are important cellular constituents involved in the regulation of cell growth and differentiation. Their intracellular levels are regulated by a multitude of mechanisms affecting their synthesis, degradation, uptake and excretion. As a result of the application of molecular biology techniques, some of these mechanisms are presently being unravelled, and are providing a basis for the rational development of novel agents effective against proliferative disorders and various parasitic diseases. © 1990.

引用

页码：153 / 158

页数：6

共 32 条

[1] GENE-EXPRESSION OF ORNITHINE DECARBOXYLASE IN L1210 LEUKEMIA-CELLS EXPOSED TO DL-2-DIFLUOROMETHYLORNITHINE IN THE PRESENCE OF CADAVERINE [J].