ACUTE TOXICITY OF FLUORINATED ETHER ANESTHETICS - ROLE OF 2,2,2-TRIFLUOROETHANOL AND OTHER METABOLITES

被引：25

作者：

MURPHY, MJ ^{[1
]}

DUNBAR, DA ^{[1
]}

KAMINSKY, LS ^{[1
]}

机构：

[1] NEW YORK STATE DEPT HLTH, CTR LABS & RES, ALBANY, NY 12201 USA

来源：

TOXICOLOGY AND APPLIED PHARMACOLOGY | 1983年 / 71卷 / 01期

关键词：

D O I：

10.1016/0041-008X(83)90047-9

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

引用

页码：84 / 92

页数：9

共 16 条

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[12] ROLE OF HEPATIC-MICROSOMAL CYTOCHROME-P-450 IN THE TOXICITY OF FLUORINATED ETHER ANESTHETICS [J].

MURPHY, MJ ;

DUNBAR, DA ;

KAMINSKY, LS .

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[13] DESTRUCTION OF HIGHLY PURIFIED CYTOCHROMES P-450 ASSOCIATED WITH METABOLISM OF FLUORINATED ETHER ANESTHETICS [J].

MURPHY, MJ ;

DUNBAR, DA ;

GUENGERICH, FP ;

KAMINSKY, LS .

ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 1981, 212 (02) :360-369

[14]

PATEL JM, 1980, DRUG METAB DISPOS, V8, P305

[15] FLUOROALKYL- AND 3-(FLUOROALKOXY)PROPYLPOLYSILOXANES [J].

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JOURNAL OF ORGANIC CHEMISTRY, 1961, 26 (08) :2943-&

[16] ISOLATION OF RAT-LIVER MICROSOMES BY GEL-FILTRATION [J].

TANGEN, O ;

JONSSON, J ;

ORRENIUS, S .

ANALYTICAL BIOCHEMISTRY, 1973, 54 (02) :597-603

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