SYNTHESIS OF ALPHA-CYANO-BETA-FLUORO-ALPHA-HYDROXYESTERS

被引：7

作者：

AMMADI, F ^{[1
]}

CHAABOUNI, MM ^{[1
]}

AMRI, H ^{[1
]}

BAKLOUTI, A ^{[1
]}

机构：

[1] FAC SCI TUNIS,CHIM ORGAN STRUCT LAB,CAMPUS UNIV,1060 TUNIS,TUNISIA

来源：

SYNTHETIC COMMUNICATIONS | 1993年 / 23卷 / 17期

关键词：

D O I：

10.1080/00397919308011124

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The ring opening fluorination of glycidic gem-cyanoesters was achieved by action of pyridine polyhydrofluoride at 25-degrees-C in dichloromethane. The regioselective nucleophilic substitution reaction allows the synthesis of a new class of fluorohydrins with OH, CN and CO2R on the same carbon atom.

引用

页码：2389 / 2395

页数：7

共 13 条

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