EFFECT ON HUMAN LIVER GLYCOSIDASES AND SHORT SYNTHESES OF 1-ALPHA,2-ALPHA,6-ALPHA,7-ALPHA,7A-BETA-1,2,6,7-TETRAHYDROXYPYRROLIZIDINE FROM D-GLYCERO-D-GULO-HEPTONO-1,4-LACTONE

被引：14

作者：

COLLIN, WF

FLEET, GWJ

HARALDSSON, M

DIBELLO, IC

WINCHESTER, B

机构：

[1] UNIV OXFORD,OXFORD CTR MOLEC SCI,OXFORD OX1 3QY,ENGLAND

[2] UNIV LONDON,INST CHILD HLTH,DEPT CLIN BIOCHEM,LONDON WC1N 1EH,ENGLAND

来源：

CARBOHYDRATE RESEARCH | 1990年 / 202卷

关键词：

D O I：

10.1016/0008-6215(90)84074-5

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The synthesis of 1a,2a,6a,7a,7aβ-1,2,6,7-tetrahydroxypyrrolizidine (1) from d-glycero-d-gulo-heptono-1,4-lactone (6) by two different routes is reported. The effects of 1 on the inhibition of 15 human liver glycosidases are described. © 1990.

引用

页码：105 / 116

页数：12

共 26 条

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