SYNTHESIS OF OPTICALLY-ACTIVE 2-FURYLMETHANOLS AS USEFUL CHIRAL BUILDING-BLOCKS AND ITS APPLICATION TO THE SYNTHESIS OF (5R,6S)-6-ACETOXYHEXADECAN-5-OLIDE AND (+)-DISPARLURE

被引：60

作者：

KAMETANI, T ^{[1
]}

TSUBUKI, M ^{[1
]}

TATSUZAKI, Y ^{[1
]}

HONDA, T ^{[1
]}

机构：

[1] HOSHI UNIV,INST MED CHEM,EBARA 2-4-41,SHINAGAWA KU,TOKYO 142,JAPAN

来源：

JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1 | 1990年 / 03期

关键词：

D O I：

10.1039/p19900000639

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Kinetic resolution of racemic secondary 2-furylmethanols using catalytic amounts of the titanium(iv)-tartrate complex was achieved successfully, providing optically active 2-furylmethanols (80->98% ee) and corresponding pyranones. (S)-1-(2-Furyl)undecanol (1f) was utilised as a chiral building block in the synthesis of (5R,6S)-6-acetoxyhexadecan-5-olide and (+)-disparlure.

引用

页码：639 / 646

页数：8

共 61 条

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