NEURONS DISSOCIATED FROM NEOCORTEX FIRE WITH BURST AND REGULAR TRAINS OF SPIKES

被引：9

作者：

GUATTEO, E

BACCI, A

FRANCESCHETTI, S

AVANZINI, G

WANKE, E

机构：

[1] UNIV MILAN,DIPARTIMENTO FISIOL & BIOCHIM GEN,I-20133 MILAN,ITALY

[2] IST NEUROCHIRURG C BESTA,MILAN,ITALY

来源：

NEUROSCIENCE LETTERS | 1994年 / 175卷 / 1-2期

关键词：

NEOCORTEX; BURSTING; FIRING CHARACTERISTIC; DISSOCIATED NEURON;

D O I：

10.1016/0304-3940(94)91093-6

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Neurons acutely dissociated from neocortex slices of 14-16-day-old rats were patch-clamped in physiological conditions. Different pyramidal cells, spontaneously or in response to current steps, generate regular spiking and intrinsically bursting behaviour during long periods of time. We show that typical firing properties recorded in somatosensory neocortex Slices are preserved in dissociated pyramidal neurons originating from the slices themselves, thus, providing a way for the related characterization of biophysical properties of currents in identified subtypes of pyramidal neurons.

引用

页码：117 / 120

页数：4

共 14 条

[1] SYNCHRONIZED EXCITATION AND INHIBITION DRIVEN BY INTRINSICALLY BURSTING NEURONS IN NEOCORTEX [J].