PHAGOCYTE RECOGNITION OF CELLS UNDERGOING APOPTOSIS

被引：972

作者：

SAVILL, J

FADOK, V

HENSON, P

HASLETT, C

机构：

[1] NATL JEWISH CTR IMMUNOL & RESP MED, DENVER, CO 80206 USA

[2] UNIV EDINBURGH, CITY HOSP, DEPT MED, RESP MED UNIT, EDINBURGH EH10 5SB, SCOTLAND

来源：

IMMUNOLOGY TODAY | 1993年 / 14卷 / 03期

基金：

英国惠康基金;

关键词：

D O I：

10.1016/0167-5699(93)90215-7

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

A key feature of apoptosis is that cells undergoing this programmed form of death are recognized by phagocytes and ingested while still intact, protecting tissues from the potentially harmful consequences of exposure to the contents of the dying cells. This article reviews recent data which indicate that phagocyte recognition of apoptotic cells as 'senescent-self' involves at least three classes of receptors on the phagocyte surface, while apoptotic cells may display their 'edible' status in a number of different ways.

引用

页码：131 / 136

页数：6

共 46 条

[41] THE EMBRYONIC-CELL LINEAGE OF THE NEMATODE CAENORHABDITIS-ELEGANS [J].