STEREOSPECIFIC DEHYDRATIVE ALKYLATION OF BIS-SULFONES - SYNTHESIS OF A LESSER TEA TORTRIX PHEROMONE(1)

被引：47

作者：

YU, JR ^{[1
]}

CHO, HS ^{[1
]}

FALCK, JR ^{[1
]}

机构：

[1] UNIV TEXAS,SW MED CTR,DEPT PHARMACOL,DALLAS,TX 75235

来源：

JOURNAL OF ORGANIC CHEMISTRY | 1993年 / 58卷 / 22期

关键词：

D O I：

10.1021/jo00074a010

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The intra- and intermolecular condensation of alcohols with bis-sulfone methylenes, i.e., dehydrative alkylation, using DEAD and Ph3P proceeds stereospecifically at room temperature under essentially neutral conditions affording good to excellent yields of alkylation/annulation products.

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页码：5892 / 5894

页数：3

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