THE IC50 - AN EXACTLY DEFINED MEASURE OF ANTIBIOTIC-SENSITIVITY

被引：46

作者：

SOOTHILL, JS ^{[1
]}

WARD, R ^{[1
]}

GIRLING, AJ ^{[1
]}

机构：

[1] UNIV BIRMINGHAM,SCH MATH & STAT,BIRMINGHAM B15 2TT,W MIDLANDS,ENGLAND

来源：

JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY | 1992年 / 29卷 / 02期

关键词：

D O I：

10.1093/jac/29.2.137

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

The concentration of gentamicin that inhibits the growth of half of an inoculum of Pseudomonas aeruginosa (IC50) was estimated by doing viable bacterial counts with varying concentrations of gentamicin and fitting a probit inhibition curve to the results. This is a more precisely defined measure than the MIC and its standard error is readily calculable. © 1992 by The British Society for Antimicrobial Chemotherapy.

引用

页码：137 / 139

页数：3