A RATIONAL NOMENCLATURE FOR VERTEBRATE HOMEOBOX (HOX) GENES

被引：82

作者：

SCOTT, MP ^{[1
]}

机构：

[1] STANFORD UNIV,MED CTR,SCH MED,DEPT GENET,STANFORD,CA 94305

来源：

NUCLEIC ACIDS RESEARCH | 1993年 / 21卷 / 08期

关键词：

D O I：

10.1093/nar/21.8.1687

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Developmental fates along the anterior-posterior axes of animals are controlled by clustered homeotic genes which in vertebrates are called Hox genes. The gene clusters are similar and probably functionally homologous in animals as different as nematodes, files, and mammals. A new set of names for Hox genes was recently agreed upon by many workers in the field. Remarkably, the order of the Hox genes along the chromosome reflects where they are expressed along the body axis1. This simple principle is reflected in the new nomenclature system.

引用

页码：1687 / 1688

页数：2

共 9 条

[1] HOX GENE ACTIVATION BY RETINOIC ACID [J].

BONCINELLI, E ;

SIMEONE, A ;

ACAMPORA, D ;

MAVILIO, F .

TRENDS IN GENETICS, 1991, 7 (10) :329-334

[2] THE STRUCTURAL AND FUNCTIONAL-ORGANIZATION OF THE MURINE HOX GENE FAMILY RESEMBLES THAT OF DROSOPHILA HOMEOTIC GENES [J].

DUBOULE, D ;

DOLLE, P .

EMBO JOURNAL, 1989, 8 (05) :1497-1505

[3]

GEHRING WJ, 1992, TRENDS BIOCHEM SCI, V17, P1277

[4] THE MURINE AND DROSOPHILA HOMEOBOX GENE COMPLEXES HAVE COMMON FEATURES OF ORGANIZATION AND EXPRESSION [J].

GRAHAM, A ;

PAPALOPULU, N ;

KRUMLAUF, R .

CELL, 1989, 57 (03) :367-378

[5]

Kaufman T C, 1990, Adv Genet, V27, P309

[6] GENE COMPLEX CONTROLLING SEGMENTATION IN DROSOPHILA [J].

LEWIS, EB .

NATURE, 1978, 276 (5688) :565-570

[7] HOMEOBOX GENES AND AXIAL PATTERNING [J].

MCGINNIS, W ;

KRUMLAUF, R .

CELL, 1992, 68 (02) :283-302

[8] VERTEBRATE HOMEOBOX GENE NOMENCLATURE [J].

SCOTT, MP .

CELL, 1992, 71 (04) :551-553

[9] THE STRUCTURE AND FUNCTION OF THE HOMEODOMAIN [J].

SCOTT, MP ;

TAMKUN, JW ;

HARTZELL, GW .

BIOCHIMICA ET BIOPHYSICA ACTA, 1989, 989 (01) :25-48

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