CYTOCHROME-P-450 - CATALYZED FORMATION OF DELTA-4-VPA, A TOXIC METABOLITE OF VALPROIC ACID

被引:249
作者
RETTIE, AE
RETTENMEIER, AW
HOWALD, WN
BAILLIE, TA
机构
[1] UNIV WASHINGTON,SCH PHARM,DEPT MED CHEM,SEATTLE,WA 98195
[2] UNIV WASHINGTON,SCH PHARM,DEPT PHARMACEUT,SEATTLE,WA 98195
关键词
D O I
10.1126/science.3101178
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
引用
收藏
页码:890 / 893
页数:4
相关论文
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