THE SQUALESTATINS, NOVEL INHIBITORS OF SQUALENE SYNTHASE PRODUCED BY A SPECIES OF PHOMA .5. MINOR METABOLITES

被引:42
作者
BLOWS, WM [1 ]
FOSTER, G [1 ]
LANE, SJ [1 ]
NOBLE, D [1 ]
PIERCEY, JE [1 ]
SIDEBOTTOM, PJ [1 ]
WEBB, G [1 ]
机构
[1] GLAXO GRP RES LTD,RES & DEV,DEPT STRUCT CHEM,GREENFORD UB6 0HE,MIDDX,ENGLAND
关键词
D O I
10.7164/antibiotics.47.740
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
The isolation and structure determination by H-1 and C-13 NMR and MS of 24 novel squalestatins from cultures of Phoma sp. C2932 is described.
引用
收藏
页码:740 / 754
页数:15
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