THIOUREA PREVENTS CYTO-TOXICITY AND MUTAGENICITY, BUT NOT SISTER-CHROMATED EXCHANGES IN V79 CELLS TREATED WITH CIS-DIAMINEDICHLOROPLATINUM(II)

被引：29

作者：

BRADLEY, MO ^{[1
]}

PATTERSON, S ^{[1
]}

ZWELLING, LA ^{[1
]}

机构：

[1] NCI,DIV CANC TREATMENT,PROGRAM DEV THERAPEUT,MOLEC PHARMACOL LAB,BETHESDA,MD 20205

来源：

MUTATION RESEARCH | 1982年 / 96卷 / 01期

关键词：

D O I：

10.1016/0027-5107(82)90017-3

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

引用

页码：67 / 74

页数：8

共 14 条

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[2]

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[4] RELATIONSHIPS BETWEEN SISTER CHROMATID EXCHANGE AND MUTAGENICITY, TOXICITY AND DNA DAMAGE [J].

BRADLEY, MO ;

HSU, IC ;

HARRIS, CC .

NATURE, 1979, 282 (5736) :318-320

[5] THIOUREA REVERSES CROSS-LINKS AND RESTORES BIOLOGICAL-ACTIVITY IN DNA TREATED WITH DICHLORODIAMINOPLATINUM(II) [J].

FILIPSKI, J ;

KOHN, KW ;

PRATHER, R ;

BONNER, WM .

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[6]

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[7]

HEFLICH RH, 1981, ENVIRON MUTAGEN, V3, P338

[8]

MYHR BC, 1975, GENETICS, V80, P157

[9] NEW GIEMSA METHOD FOR DIFFERENTIAL STAINING OF SISTER CHROMATIDS [J].

PERRY, P ;

WOLFF, S .

NATURE, 1974, 251 (5471) :156-158

[10]

PRESTAYKO AW, 1980, CIS PLATIN CURRENT S, P17

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