SYNTHESIS OF TERTIARY ALCOHOL FROM SECONDARY ALCOHOL VIA INTRAMOLECULAR C-H INSERTION OF ALKYLIDENECARBENE

被引：18

作者：

OHIRA, S

NODA, I

MIZOBATA, T

YAMATO, M

机构：

[1] Department of Biological Chemistry, Faculty of Science, Okayama University of Science, Okayama

来源：

TETRAHEDRON LETTERS | 1995年 / 36卷 / 19期

关键词：

D O I：

10.1016/0040-4039(95)00545-N

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Alkylidenecarbene generated by the reaction of dimethyl (diazomethyl)phosphonate and pyruvate did not render a 1,5 C-H insertion, but gave an unusual product. In contrast, 2-oxopropyl ether was cleanly transformed into a cyclized product, from which functionalized tertiary alcohol was derived.

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页码：3375 / 3376

页数：2

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