ECHOVIRUS-1 INTERACTION WITH THE ISOLATED VLA-2 I-DOMAIN

被引：32

作者：

KING, SL

CUNNINGHAM, JA

FINBERG, RW

BERGELSON, JM

机构：

来源：

JOURNAL OF VIROLOGY | 1995年 / 69卷 / 05期

关键词：

D O I：

10.1128/JVI.69.5.3237-3239.1995

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

The isolated I domain of the integrin VLA-2, produced as a bacterial fusion protein, specifically bound echovirus 1 and prevented virus attachment to cells. These results demonstrate that the receptor structures critical for virus attachment are contained solely within the VLA-2 I domain and that soluble receptor fragments are capable of preventing infection.

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页码：3237 / 3239

页数：3

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