CADHERIN-MEDIATED CELL CELL-ADHESION AND NEUROGENESIS

被引：22

作者：

TAKEICHI, M

INUZUKA, H

SHIMAMURA, K

MATSUNAGA, M

NOSE, A

机构：

[1] Department of Biophysics, Faculty of Science, Kyoto University, Kyoto

来源：

NEUROSCIENCE RESEARCH | 1990年

关键词：

cDNA transfection; Cell adhesion molecule; Cell sorting; Neural retina; Neurite outgrowth; Transmembrane protein;

D O I：

10.1016/0921-8696(90)90036-3

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Cadherins constitute a molecular family which confers adhesive specificities on cells. Their expression is spatio-temporally regulated in embryos and the multiple types of cadherins are expressed in the nervous system. The inhibition of cadherin action with antibodies resulted in the perturbation of the histogenesis of neural tissues. The sites for determining the binding specificities of cadherins reside in their amino terminal 113 amino acid region. Possible roles of cadherins associated with these properties in neurogenesis are discussed. © 1990.

引用

页码：S92 / S96

页数：5

共 9 条

[1] AXON GUIDANCE AND THE PATTERNING OF NEURONAL PROJECTIONS IN VERTEBRATES [J].