ENANTIODIFFERENTIATION OF GAMMA-LACTONES AND DELTA-LACTONES BY GAS-CHROMATOGRAPHIC SEPARATION OF DIASTEREOMERIC CARBAMOYLOXY CARBOXAMIDE DERIVATIVES

被引：5

作者：

ENGEL, KH

ALBRECHT, W

HEIDLAS, J

机构：

[1] Technische Universität Berlin, Institut für Biotechnologie, Fachgebiet Chemisch-technische Analyse, Berlin 65, Seestrasse 13

来源：

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY | 1990年 / 38卷 / 01期

关键词：

D O I：

10.1021/jf00091a053

中图分类号：

S [农业科学];

学科分类号：

09 ;

摘要：

Enantiodifferentiation of chiral γ- and δ-lactones has been achieved by capillary gas chromatographic separation of diastereomeric 4- and 5-[(R)-[(l-phenylethyl)carbamoyl]oxy] N-butylcarboxamides. The derivatization procedure involves (1) ring-opening of lactones to hydroxycarboxamides by heating with butylamine and (2) subsequent conversion to diastereomeric carbamates by reaction with (R)- (+)-1-phenylethyl isocyanate. High separation factors were determined for the complete series of C5-C12 γ-lactones and C6-C12 δ-lactones, naturally occurring (trace) constituents of many fruits and vegetables. © 1990, American Chemical Society. All rights reserved.

引用

页码：244 / 247

页数：4

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