CHARACTERIZATION OF MEASLES VIRUSES ISOLATED AFTER MEASLES VACCINATION

被引：49

作者：

KOBUNE, F

FUNATU, M

TAKAHASHI, H

FUKUSHIMA, M

KAWAMOTO, A

IIZUKA, S

SAKATA, H

YAMAZAKI, S

ARITA, M

WENBO, X

ZHANG, LB

机构：

[1] CHEMOSEROTHERAPEUT RES INST,KUMAMOTO,JAPAN

[2] TOTTORI PREFECTURAL INST PUBL HLTH,TOTTORI,JAPAN

[3] SHIMANE PREFECTURAL INST PUBL HLTH & ENVIRONM SCI,MATSUE,SHIMANE,JAPAN

[4] CHINESE ACAD PREVENT MED,BEIJING,PEOPLES R CHINA

来源：

VACCINE | 1995年 / 13卷 / 04期

关键词：

MEASLES VACCINE; SIDE-REACTION; MEASLES VIRUS ISOLATION;

D O I：

10.1016/0264-410X(95)98259-D

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Seven measles virus (MV) strains were isolated from children who developed clinical signs of fever and rash 3-9 days after measles vaccination. The nucleotide sequence of the H gene, the molecular size of the H protein, the haemadsorption activity on African green monkey red blood cells, and antigenicity as determined by virus neutralization revealed that one strain was of the vaccine type and the remaining six were the wild virus type, Isolation of the virus directly from patients suspected of a vaccine-induced side-reaction and subsequent characterization of such isolated virus may be useful in differentiation between vaccine-induced side-reactions and natural measles.

引用

页码：370 / 372

页数：3

共 11 条

[1]

ENDERS JF, 1954, P SOC EXP BIOL MED, V86, P277, DOI 10.3181/00379727-86-21073

[2]

HOSINO M, 1982, CLIN VIROL, V10, P235

[3] MARMOSET LYMPHOBLASTOID-CELLS AS A SENSITIVE HOST FOR ISOLATION OF MEASLES-VIRUS [J].