CHROMOSOME-ABNORMALITIES OF GASTRIC-CANCER DETECTED IN CANCEROUS EFFUSIONS

被引：9

作者：

MISAWA, S

HORIIKE, S

TANIWAKI, M

TSUDA, S

OKUDA, T

KASHIMA, K

ABE, T

SUGIHARA, H

NORIKI, S

FUKUDA, M

机构：

[1] KYOTO PREFECTURAL UNIV MED,DEPT HYG,KAMIGYO KU,KYOTO 602,JAPAN

[2] KYOTO PREFECTURAL UNIV MED,DEPT PATHOL 2,KAMIGYO KU,KYOTO 602,JAPAN

[3] FUKUI MED SCH,DEPT PATHOL 1,FUKUI 91011,JAPAN

来源：

JAPANESE JOURNAL OF CANCER RESEARCH | 1990年 / 81卷 / 02期

关键词：

Chromosomes; Effusion; Gastric cancer; Human;

D O I：

10.1111/j.1349-7006.1990.tb02541.x

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

The chromosomes were examined in cancerous effusions obtained from 7 patients with gastric cancer. In 1 patient, the modal chromosome number was 46 with a normal chromosome complement in the majority of the cells examined. The other 6 patients revealed numerical and structural aberrations. Among the structural rearrangements detected, chromosome 3 was involved in the short arm and in the long arm, each in three patients; bands p25, q21, q23, and q27 were recurrently involved and a band q23 was lost in 3 patients. Rearrangements of chromosome 5 in the long arm and of chromosome 17 at or near the centromere were also observed in three patients each. Gains of chromosome 7 was seen in 5 patients and of chromosome 13 in 4. Some of these alterations may be specific for gastric cancer. Copyright © 1990, Wiley Blackwell. All rights reserved

引用

页码：148 / 152

页数：5

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