EVALUATION OF THE CRITERIA USED TO MAKE THE DIAGNOSIS OF NONMETASTATIC GESTATIONAL TROPHOBLASTIC NEOPLASIA

被引:26
作者
KOHORN, EI
机构
[1] Department of Obstetrics/Gynecology, Yale Trophoblastic Disease Center, Yale University School of Medicine, New Haven, CT 06510
关键词
D O I
10.1006/gyno.1993.1025
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
The administration of chemotherapy following hydatidiform mole evacuation implies a diagnosis of trophoblastic neoplasia. A review of the literature and an analysis of a questionnaire sent to physicians treating trophoblastic disease shows that the criteria used to make this decision vary significantly. The factors that make it important to arrive at a consensus are discussed. Alternative investigations other than hCG that may distinguish neoplasia such as doppler flow ultrasound and magnetic resonance imaging are examined critically. A definition of neoplasia is presented that relates tumor load as measured by hCG to the length of hCG plateau. The changing criteria for distinguishing metastasis are discussed. © 1993 Academic Press, Inc.
引用
收藏
页码:139 / 147
页数:9
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