SYNTHESIS OF 2,4-DIDEOXY-D-ERYTHRO-HEXOPYRANOSE - AN INTERMEDIATE FOR SYNTHESIS OF THE LACTONE MOIETY OF INHIBITORS OF HYDROXYMETHYLGLUTARYL-COENZYME-A REDUCTASE

被引：7

作者：

HO, PT

CHUNG, S

机构：

来源：

CARBOHYDRATE RESEARCH | 1984年 / 125卷 / 02期

关键词：

D O I：

10.1016/0008-6215(84)85167-8

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

页码：318 / 322

页数：5

共 10 条

[1] MEVINOLIN - A HIGHLY POTENT COMPETITIVE INHIBITOR OF HYDROXYMETHYLGLUTARYL-COENZYME-A REDUCTASE AND A CHOLESTEROL-LOWERING AGENT [J].

ALBERTS, AW ;

CHEN, J ;

KURON, G ;

HUNT, V ;

HUFF, J ;

HOFFMAN, C ;

ROTHROCK, J ;

LOPEZ, M ;

JOSHUA, H ;

HARRIS, E ;

PATCHETT, A ;

MONAGHAN, R ;

CURRIE, S ;

STAPLEY, E ;

ALBERSSCHONBERG, G ;

HENSENS, O ;

HIRSHFIELD, J ;

HOOGSTEEN, K ;

LIESCH, J ;

SPRINGER, J .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES, 1980, 77 (07) :3957-3961

[2] RULES FOR RING-CLOSURE [J].

BALDWIN, JE .

JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS, 1976, (18) :734-736

[3] NEW METHOD FOR DEOXYGENATION OF SECONDARY ALCOHOLS [J].

BARTON, DHR ;

MCCOMBIE, SW .

JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1, 1975, (16) :1574-1585

[4] CRYSTAL AND MOLECULAR-STRUCTURE OF COMPACTIN, A NEW ANTIFUNGAL METABOLITE FROM PENICILLIUM-BREVICOMPACTUM [J].

BROWN, AG ;

SMALE, TC ;

KING, TJ ;

HASENKAMP, R ;

THOMPSON, RH .

JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1, 1976, (11) :1165-1173

[5]

GROBEL BT, 1977, SYNTHESIS-STUTTGART, P357

[6] HYPOLIPIDEMIC EFFECTS IN MONKEYS OF ML-236B, A COMPETITIVE INHIBITOR OF 3-HYDROXY-3-METHYLGLUTARYL COENZYME-A REDUCTASE [J].

KURODA, M ;

TSUJITA, Y ;

TANZAWA, K ;

ENDO, A .

LIPIDS, 1979, 14 (06) :585-589

[7] METHYL 3-0-BENZYL-2,4,6-TRIDEOXY-6-IODO-ALPHA-D-ERYTHRO-HEXOPYRANOSIDE, A CHIRAL SYNTHON FOR THE SYNTHESIS OF INHIBITORS OF HMG-COA REDUCTASE [J].

PRUGH, JD ;

DEANA, AA .

TETRAHEDRON LETTERS, 1982, 23 (03) :281-284

[8] PHOSPHORYLATED SUGARS .X. A SIMPLE SYNTHESIS OF 3-DEOXY-D-ERYTHRO-PENTSOE 5-(DIHYDROGEN PHOSPHATE) [J].

SZABO, P ;

SZABO, L .

JOURNAL OF THE CHEMICAL SOCIETY, 1965, (APR) :2944-&

[9] THERAPEUTIC EFFECTS OF ML-236B IN PRIMARY HYPERCHOLESTEROLEMIA [J].

YAMAMOTO, A ;

SUDO, H ;

ENDO, A .

ATHEROSCLEROSIS, 1980, 35 (03) :259-266

[10] MEVINIC ACIDS AND ANALOGS - PREPARATION OF A KEY CHIRAL INTERMEDIATE [J].

YANG, YL ;

FALCK, JR .

TETRAHEDRON LETTERS, 1982, 23 (42) :4305-4308

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