MECHANISMS AND CATALYSTS OF DISULFIDE BOND FORMATION IN PROTEINS

被引：93

作者：

CREIGHTON, TE

ZAPUN, A

DARBY, NJ

机构：

来源：

TRENDS IN BIOTECHNOLOGY | 1995年 / 13卷 / 01期

关键词：

D O I：

10.1016/S0167-7799(00)88896-4

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

The formation of disulphide bonds is an important co- and post-translational event in the biosynthesis of many extracellular proteins that is often coupled to protein folding. Progress in understanding how disulphide bonds form in model proteins provides insight into how the process can be manipulated to optimize the production of engineered proteins.

引用

页码：18 / 23

页数：6

共 35 条

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