1-(3-CYANO-2,3-DIDEOXY-BETA-D-ERYTHRO-PENTOFURANOSYL)THYMINE (CYANOTHYMIDINE) - SYNTHESIS AND ANTIVIRAL EVALUATION AGAINST HUMAN IMMUNODEFICIENCY VIRUS

被引：26

作者：

GREENGRASS, CW

HOOPLE, DWT

STREET, SDA

HAMILTON, F

MARRIOTT, MS

BORDNER, J

DALGLEISH, AG

MITSUYA, H

BRODER, S

机构：

[1] PFIZER INC,CENT RES LABS,GROTON,CT 06340

[2] CLIN RES CTR,HARROW HA1 3UJ,MIDDX,ENGLAND

[3] NCI,BETHESDA,MD 20892

来源：

JOURNAL OF MEDICINAL CHEMISTRY | 1989年 / 32卷 / 03期

关键词：

D O I：

10.1021/jm00123a019

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

引用

页码：618 / 622

页数：5

共 32 条

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[20] INHIBITION OF HIV-ASSOCIATED REVERSE-TRANSCRIPTASE BY SUGAR-MODIFIED DERIVATIVES OF THYMIDINE 5'-TRIPHOSPHATE IN COMPARISON TO CELLULAR DNA POLYMERASE-ALPHA AND POLYMERASE-BETA
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