ANTIGENIC VARIATION OF PSEUDORABIES VIRUS GLYCOPROTEIN-GII AND GLYCOPROTEIN-GIII DEMONSTRATED BY NEUTRALIZING MONOCLONAL-ANTIBODIES

被引：10

作者：

YAMADA, S

IMADA, T

NISHIMORI, T

SEKIKAWA, K

SHIMIZU, M

机构：

[1] Second Research Division, National Institute of Animal Health, Ibaraki

来源：

ARCHIVES OF VIROLOGY | 1991年 / 119卷 / 3-4期

关键词：

D O I：

10.1007/BF01310677

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Antigenic variation of pseudorabies virus glycoprotein g II was demonstrated in field isolates by neutralizing monoclonal antibodies. Mutants capable of avoiding neutralization by the monoclonal antibodies specific for glycoproteins g II and g Ill could be obtained from the parent virus by mutagenesis.

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页码：285 / 290

页数：6

相关论文

共 15 条

[1] ROLE OF GLYCOPROTEINS OF PSEUDORABIES VIRUS IN ELICITING NEUTRALIZING ANTIBODIES [J].

BENPORAT, T ;

DEMARCHI, JM ;

LOMNICZI, B ;

KAPLAN, AS .

VIROLOGY, 1986, 154 (02) :325-334

[2]

Fukusho A., 1981, Bulletin of the National Institute of Animal Health, Japan, P5

[3] CHARACTERIZATION OF THE ENVELOPE PROTEINS OF PSEUDORABIES VIRUS [J].

HAMPL, H ;

BENPORAT, T ;

EHRLICHER, L ;

HABERMEHL, KO ;

KAPLAN, AS .

JOURNAL OF VIROLOGY, 1984, 52 (02) :583-590

[4] ANTIGENIC VARIANTS OF HERPES-SIMPLEX VIRUS SELECTED WITH GLYCOPROTEIN-SPECIFIC MONOCLONAL-ANTIBODIES [J].

HOLLAND, TC ;

MARLIN, SD ;

LEVINE, M ;

GLORIOSO, J .

JOURNAL OF VIROLOGY, 1983, 45 (02) :672-682

[5] LOCATION OF THE STRUCTURAL GENE OF PSEUDORABIES VIRUS GLYCOPROTEIN COMPLEX GII [J].

METTENLEITER, TC ;

LUKACS, N ;

THIEL, HJ ;

SCHREURS, C ;

RZIHA, HJ .

VIROLOGY, 1986, 152 (01) :66-75

[6]

METTENLEITER TC, 1985, J VIROL, V56, P307, DOI 10.1128/JVI.56.1.307-311.1985

[7] DIFFERENTIATION OF PSEUDORABIES (AUJESZKYS DISEASE) VIRUS-STRAINS BY RESTRICTION ENDONUCLEASE ANALYSIS [J].

PAUL, PS ;

MENGELING, WL ;

PIRTLE, EC .

ARCHIVES OF VIROLOGY, 1982, 73 (02) :193-198

[8] DELETIONS IN VACCINE STRAINS OF PSEUDORABIES VIRUS AND THEIR EFFECT ON SYNTHESIS OF GLYCOPROTEIN GP63 [J].

PETROVSKIS, EA ;

TIMMINS, JG ;

GIERMAN, TM ;

POST, LE .

JOURNAL OF VIROLOGY, 1986, 60 (03) :1166-1169

[9] MAPPING AND SEQUENCE OF THE GENE FOR THE PSEUDORABIES VIRUS GLYCOPROTEIN WHICH ACCUMULATES IN THE MEDIUM OF INFECTED-CELLS [J].

REA, TJ ;

TIMMINS, JG ;

LONG, GW ;

POST, LE .

JOURNAL OF VIROLOGY, 1985, 54 (01) :21-29

[10] THE PSEUDORABIES VIRUS-GII GENE IS CLOSELY RELATED TO THE GB GLYCOPROTEIN GENE OF HERPES-SIMPLEX VIRUS [J].

ROBBINS, AK ;

DORNEY, DJ ;

WATHEN, MW ;

WHEALY, ME ;

GOLD, C ;

WATSON, RJ ;

HOLLAND, LE ;

WEED, SD ;

LEVINE, M ;

GLORIOSO, JC ;

ENQUIST, LW .

JOURNAL OF VIROLOGY, 1987, 61 (09) :2691-2701