ANTIGENIC VARIATION OF PSEUDORABIES VIRUS GLYCOPROTEIN-GII AND GLYCOPROTEIN-GIII DEMONSTRATED BY NEUTRALIZING MONOCLONAL-ANTIBODIES

被引：10

作者：

YAMADA, S

IMADA, T

NISHIMORI, T

SEKIKAWA, K

SHIMIZU, M

机构：

[1] Second Research Division, National Institute of Animal Health, Ibaraki

来源：

ARCHIVES OF VIROLOGY | 1991年 / 119卷 / 3-4期

关键词：

D O I：

10.1007/BF01310677

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Antigenic variation of pseudorabies virus glycoprotein g II was demonstrated in field isolates by neutralizing monoclonal antibodies. Mutants capable of avoiding neutralization by the monoclonal antibodies specific for glycoproteins g II and g Ill could be obtained from the parent virus by mutagenesis.

引用

页码：285 / 290

页数：6

共 15 条

[11] CHARACTERIZATION OF A PSEUDORABIES VIRUS GLYCOPROTEIN GENE WITH HOMOLOGY TO HERPES-SIMPLEX VIRUS TYPE-1 AND TYPE-2 GLYCOPROTEIN-C [J].