THE ALUMINUM AMALGAM REDUCTION OF 2-NITROALKANOLS PROMOTED BY ULTRASOUND

被引：21

作者：

FITCH, RW ^{[1
]}

LUZZIO, FA ^{[1
]}

机构：

[1] UNIV LOUISVILLE,DEPT CHEM,LOUISVILLE,KY 40292

来源：

TETRAHEDRON LETTERS | 1994年 / 35卷 / 33期

关键词：

D O I：

10.1016/0040-4039(94)88062-X

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The sonochemical promoted aluminum amalgam reduction of 2-nitroalkanols provides an improved yield and accelerated conversion to the corresponding amino alcohols when compared to the nonultrasound (benchtop) reductions. The appearance of by-product hydroxylamines is minimized during the ultrasound promoted reaction. The product amino alcohols were conveniently acylated in situ with promotion by ultrasound thus affording the N-acyl derivatives in the same operation.

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页码：6013 / 6016

页数：4

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