A FORMAL TOTAL SYNTHESIS OF 3-O-DEMETHYLFORTAMINE

被引：13

作者：

CAMBIE, RC ^{[1
]}

RENNER, ND ^{[1
]}

RUTLEDGE, PS ^{[1
]}

WOODGATE, PD ^{[1
]}

机构：

[1] UNIV AUCKLAND,DEPT CHEM,AUCKLAND,NEW ZEALAND

来源：

AUSTRALIAN JOURNAL OF CHEMISTRY | 1991年 / 44卷 / 01期

关键词：

D O I：

10.1071/CH9910061

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Rho-Benzoquinone has been converted into the substituted cyclohexenone (11) in five steps and 33% overall yield by a Diels-Alder cycloaddition-cycloreversion approach in which anthracene functions as a protecting and stereodirecting group. The elaboration of (11) in four steps to the known epoxide (22) constitutes a formal total synthesis of 3-O-demethylfortamine (2).

引用

页码：61 / 75

页数：15

共 35 条

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