CARBOXYPEPTIDASE-A - NOVEL ENZYME SUBSTRATE PRODUCT COMPLEX

被引：50

作者：

CHRISTIANSON, DW ^{[1
]}

LIPSCOMB, WN ^{[1
]}

机构：

[1] HARVARD UNIV,DEPT CHEM,GIBBS CHEM LABS,CAMBRIDGE,MA 02138

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 1987年 / 109卷 / 18期

关键词：

D O I：

10.1021/ja00252a046

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

引用

页码：5536 / 5538

页数：3

共 19 条

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[4] THE COMPLEX BETWEEN CARBOXYPEPTIDASE-A AND A POSSIBLE TRANSITION-STATE ANALOG - MECHANISTIC INFERENCES FROM HIGH-RESOLUTION X-RAY STRUCTURES OF ENZYME-INHIBITOR COMPLEXES [J].

CHRISTIANSON, DW ;

LIPSCOMB, WN .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1986, 108 (16) :4998-5003

[5] STRUCTURE OF THE COMPLEX BETWEEN AN UNEXPECTEDLY HYDROLYZED PHOSPHONAMIDATE INHIBITOR AND CARBOXYPEPTIDASE-A [J].

CHRISTIANSON, DW ;

LIPSCOMB, WN .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1986, 108 (03) :545-546

[6] MECHANISM OF CARBOXYPEPTIDASE-A - HYDRATION OF A KETONIC SUBSTRATE-ANALOG [J].

CHRISTIANSON, DW ;

DAVID, PR ;

LIPSCOMB, WN .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1987, 84 (06) :1512-1515

[7] BINDING OF A POSSIBLE TRANSITION-STATE ANALOG TO THE ACTIVE-SITE OF CARBOXYPEPTIDASE-A [J].

CHRISTIANSON, DW ;

LIPSCOMB, WN .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1985, 82 (20) :6840-6844

[8] NOVEL STRUCTURE OF THE COMPLEX BETWEEN CARBOXYPEPTIDASE-A AND A KETONIC SUBSTRATE-ANALOG [J].

CHRISTIANSON, DW ;

KUO, LC ;

LIPSCOMB, WN .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1985, 107 (26) :8281-8283

[9]

CHRISTIANSON DW, 1986, ZINC ENZYMES, P121

[10]

CHRISTIANSON DW, 1986, P NATL ACAD SCI US, V83, P7658

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