PRESENCE OF TYPE-III COLLAGEN IN DISK ATTACHMENTS OF HUMAN TEMPOROMANDIBULAR JOINTS

被引:32
作者
GAGE, JP
VIRDI, AS
TRIFFITT, JT
HOWLETT, CR
FRANCIS, MJO
机构
[1] NUFFIELD ORTHOPAED CTR,MRC,BONE RES LAB,OXFORD OX3 7LD,ENGLAND
[2] UNIV NEW S WALES,SCH PATHOL,KENSINGTON,NSW 2033,AUSTRALIA
[3] NUFFIELD ORTHOPAED CTR,NUFFIELD DEPT ORTHOPAED SURG,OXFORD OX3 7LD,ENGLAND
关键词
articular disc; collagen; fibrocartilage; temporomandibular joint;
D O I
10.1016/0003-9969(90)90044-B
中图分类号
R78 [口腔科学];
学科分类号
1003 ;
摘要
Samples of discs and disc attachments were extracted by dissociative methods and the resultant collagenous residues cleaved with cyanogen bromide. Soluble peptides thus released were characterized by their electrophoretic mobility following SDS-PAGE and by Western blot staining with specific antibodies against type I and type III collagens. Type III collagen was identified in samples taken from the posterior discal attachments. This may explain why this disc is prone to detachment and internal derangement and the high incidence of patients with temporomandibular joint dysfunction. © 1990.
引用
收藏
页码:283 / 288
页数:6
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