DIFFUSE LEPTOMENINGEAL INVOLVEMENT BY A GANGLIOGLIOMA IN A CHILD

被引：42

作者：

WACKER, MR

COGEN, PH

ETZELL, JE

DANESHVAR, L

DAVIS, RL

PRADOS, MD

机构：

[1] UNIV CALIF SAN FRANCISCO,SCH MED,DEPT PATHOL,SAN FRANCISCO,CA 94122

[2] UNIV CALIF SAN FRANCISCO,SCH MED,DEPT PEDIAT,SAN FRANCISCO,CA 94122

[3] UNIV CALIF SAN FRANCISCO,SCH MED,BRAIN TUMOR RES CTR,SAN FRANCISCO,CA 94122

来源：

JOURNAL OF NEUROSURGERY | 1992年 / 77卷 / 02期

关键词：

GANGLIOGLIOMA; LEPTOMENINGEAL TUMOR; METASTASIS; MOLECULAR GENETICS;

D O I：

10.3171/jns.1992.77.2.0302

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Gangliogliomas are tumors composed of neuronal and glial elements that typically grow slowly by expansion only. This report describes a 20-month-old girl with a ganglioglioma that extensively involved the subarachnoid space; microscopic foci of tumor were found in the brain and spinal cord. Despite chemotherapy and radiation therapy, the child died 5 months after diagnosis. Molecular genetic analysis showed loss of chromosome 17p DNA sequences in the tumor tissue.

引用

页码：302 / 306

页数：5

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