Ribosomal proteins and elongation factors

被引：55

作者：

Liljas, A ^{[1
]}

Garber, M ^{[1
]}

机构：

[1] RUSSIAN ACAD SCI, INST PROT RES, PUSHCHINO 142292, RUSSIA

来源：

CURRENT OPINION IN STRUCTURAL BIOLOGY | 1995年 / 5卷 / 06期

关键词：

D O I：

10.1016/0959-440X(95)80003-4

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Structural work on the translation machinery has recently undergone rapid progress. It is now known that six out of nine ribosomal proteins have an RNA-binding fold, and two domains of elongation factors Tu and G have very similar folds. in addition, the complex of EF-Tu with a GTP analogue and Phe-tRNA(Phe) has a structure that overlaps exceedingly well with that of EF-G GDP. These findings obviously have functional implications.

引用

页码：721 / 727

页数：7

共 59 条

[51] THE SARCIN RICIN LOOP, A MODULAR RNA [J].

SZEWCZAK, AA ;

MOORE, PB .

JOURNAL OF MOLECULAR BIOLOGY, 1995, 247 (01) :81-98

[52]

Traut R. R., 1986, STRUCTURE FUNCTION G, P286

[53] NMR ANALYSIS OF HELIX-I FROM THE 5S RNA OF ESCHERICHIA-COLI [J].

WHITE, SA ;

NILGES, M ;

HUANG, A ;

BRUNGER, AT ;

MOORE, PB .

BIOCHEMISTRY, 1992, 31 (06) :1610-1621

[54] CRYSTAL-STRUCTURE OF A PROKARYOTIC RIBOSOMAL-PROTEIN [J].

WILSON, KS ;

APPELT, K ;

BADGER, J ;

TANAKA, I ;

WHITE, SW .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1986, 83 (19) :7251-7255

[55]

WITTMANNLIEBOLD B, 1990, RIBOSOME, P598

[56] KIRROMYCIN, AN INHIBITOR OF PROTEIN-BIOSYNTHESIS THAT ACTS ON ELONGATION-FACTOR TU [J].

WOLF, H ;

CHINALI, G ;

PARMEGGIANI, A .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1974, 71 (12) :4910-4914

[57] RIBOTOXIN RECOGNITION OF RIBOSOMAL-RNA AND A PROPOSAL FOR THE MECHANISM OF TRANSLOCATION [J].

WOOL, IG ;

GLUCK, A ;

ENDO, Y .

TRENDS IN BIOCHEMICAL SCIENCES, 1992, 17 (07) :266-269

[58] FEEDBACK-REGULATION OF RIBOSOMAL-PROTEIN SYNTHESIS IN ESCHERICHIA-COLI - LOCALIZATION OF THE MESSENGER-RNA TARGET SITES FOR REPRESSOR ACTION OF RIBOSOMAL PROTEIN-L1 [J].

YATES, JL ;

NOMURA, M .

CELL, 1981, 24 (01) :243-249

[59] STRUCTURAL ASPECTS OF RIBONUCLEOPROTEIN INTERACTIONS IN RIBOSOMES [J].

YONATH, A ;

FRANCESCHI, F .

CURRENT OPINION IN STRUCTURAL BIOLOGY, 1993, 3 (01) :45-49

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