A SHORT 3-COMPONENT TOTAL SYNTHESIS OF 12-HYDROXYEICOSA-5,8,14(Z),10(E)-TETRAENOIC ACID (12-HETE) VIA THE CORRESPONDING KETONE

被引：32

作者：

COREY, EJ

KYLER, K

RAJU, N

机构：

来源：

TETRAHEDRON LETTERS | 1984年 / 25卷 / 45期

关键词：

D O I：

10.1016/S0040-4039(01)81538-0

中图分类号：

O62 [有机化学];

学科分类号：

070303 [有机化学]; 081704 [应用化学];

摘要：

引用

收藏

页码：5115 / 5118

页数：4

相关论文

共 17 条

[1]

DICYCLOHEXYLPHOSPHIDE AS AN AUXILIARY LIGAND FOR THERMALLY STABLE HETEROCUPRATES WITH CONSIDERABLY IMPROVED REACTIVITY - SOME BENEFICENT EFFECTS OF LIBR ON CUPRATE REACTIVITY [J].

BERTZ, SH ;

DABBAGH, G .

JOURNAL OF ORGANIC CHEMISTRY, 1984, 49 (06) :1119-1122

[2]

THE STEREOCHEMISTRY AND BIOSYNTHESIS OF HYBRIDALACTONE, AN EICOSANOID FROM LAURENCIA-HYBRIDA [J].

COREY, EJ ;

DE, B ;

PONDER, JW ;

BERG, JM .

TETRAHEDRON LETTERS, 1984, 25 (10) :1015-1018

[3]

TOTAL SYNTHESIS OF (S)-12-HYDROXY-5,8,14-CIS-10-TRANS-EICOSATETRAENOIC ACID (SAMUELSSONS HETE) [J].

COREY, EJ ;

NIWA, H ;

KNOLLE, J .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1978, 100 (06) :1942-1943

[4]

TOTAL SYNTHESIS OF BIOLOGICALLY-ACTIVE METABOLITES OF ARACHIDONIC-ACID - THE 2 8-HYDROXY-11,12(S,S)-EPOXYEICOSA-5,14(Z),9(E)-TRIENOIC ACIDS [J].

COREY, EJ ;

SU, WG .

TETRAHEDRON LETTERS, 1984, 25 (45) :5119-5122

[5]

TOTAL SYNTHESIS OF 12-(S)-10-HYDROXY-TRANS-11,12-EPOXYEICOSA-5,9,14-(Z)-TRIENOIC ACIDS, METABOLITES OF ARACHIDONIC-ACID IN MAMMALIAN BLOOD-PLATELETS [J].

COREY, EJ ;

KANG, J ;

LAGUZZA, BC ;

JONES, RL .

TETRAHEDRON LETTERS, 1983, 24 (45) :4913-4916

[6]

IRREVERSIBLE INHIBITION OF PROSTAGLANDIN AND LEUKOTRIENE BIOSYNTHESIS FROM ARACHIDONIC-ACID BY 11,12-DEHYDROARACHIDONIC AND 5,6-DEHYDROARACHIDONIC ACIDS, RESPECTIVELY [J].

COREY, EJ ;

MUNROE, JE .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1982, 104 (06) :1752-1754

[7]

CHEMICAL AND ENZYMIC SYNTHESES OF 5-HPETE - KEY BIOLOGICAL PRECURSOR OF SLOW-REACTING SUBSTANCE OF ANAPHYLAXIS (SRS), AND 5-HETE [J].

COREY, EJ ;

ALBRIGHT, JO ;

BARTON, AE ;

HASHIMOTO, SI .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1980, 102 (04) :1435-1436

[8]

STEREOSPECIFIC TOTAL SYNTHESIS OF 11(R)-HETE (2), LIPOXYGENATION PRODUCT OF ARACHIDONIC-ACID VIA THE PROSTAGLANDIN PATHWAY [J].

COREY, EJ ;

KANG, J .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1981, 103 (15) :4618-4619

[9]

SHORT, STEREOCONTROLLED SYNTHESES OF IRREVERSIBLE EICOSANOID BIOSYNTHESIS INHIBITORS - 5,6-DEHYDROARACHIDONIC,8,9-DEHYDROARACHIDONIC, AND 11,12-DEHYDROARACHIDONIC ACID [J].

COREY, EJ ;

KANG, J .

TETRAHEDRON LETTERS, 1982, 23 (16) :1651-1654

[10]

A NEW GENERAL SYNTHETIC ROUTE TO BRIDGED CARBOXYLIC ORTHO ESTERS [J].

COREY, EJ ;

RAJU, N .

TETRAHEDRON LETTERS, 1983, 24 (50) :5571-5574