A HIGH-RESOLUTION LINKAGE MAP OF HUMAN 9Q34.1

被引：25

作者：

HENSKE, EP

OZELIUS, L

GUSELLA, JF

HAINES, JL

KWIATKOWSKI, DJ

机构：

[1] HARVARD UNIV,BRIGHAM & WOMENS HOSP,SCH MED,DIV EXPTL MED & HEMATOL ONCOL,BOSTON,MA 02115

[2] MASSACHUSETTS GEN HOSP,NEUROGENET LAB,BOSTON,MA 02114

来源：

GENOMICS | 1993年 / 17卷 / 03期

关键词：

D O I：

10.1006/geno.1993.1376

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

A map comprising 16 distinct markers with heterozygosities of 0.61-0.92 for a 10-cM region of human 9q34.1 is presented. The map incorporates four genes and has a maximum intermarker interval of 2.1 cM. Markers were analyzed in the Venezuelan reference pedigrees and all were placed uniquely in the map with a minimum likelihood of 676:1. The map should prove useful in analysis of families segregating dystonia and tuberous sclerosis, as the DYT1 and TSC1 loci map within this region. © 1993 Academic Press, Inc.

引用

页码：587 / 591

页数：5

共 18 条

[1] BUETOW KH, 1991, AM J HUM GENET, V49, P985
[2] FRYER AE, 1987, LANCET, V1, P659
[3] A GENETIC-LINKAGE MAP OF CHROMOSOME-17
HAINES, JL
OZELIUS, LJ
MCFARLANE, H
MENON, A
TZALL, S
MARTINIUK, F
HIRSCHHORN, R
GUSELLA, JF
[J]. GENOMICS, 1990, 8 (01) : 1 - 6
[4] CHROMLOOK - AN INTERACTIVE PROGRAM FOR ERROR-DETECTION AND MAPPING IN REFERENCE LINKAGE DATA
HAINES, JL
[J]. GENOMICS, 1992, 14 (02) : 517 - 519
[5] HAINES JL, 1991, AM J HUM GENET, V49, P764
[6] A RADIATION-REDUCED HYBRID CELL-LINE CONTAINING 5 MB/17 CM OF HUMAN DNA FROM 9Q34
HENSKE, EP
OZELIUS, L
ANDERSON, MA
KWIATKOWSKI, DJ
[J]. GENOMICS, 1992, 13 (03) : 841 - 844
[7] Johnson P. H., 1992, Human Molecular Genetics, V1, P341, DOI 10.1093/hmg/1.5.341
[8] LINKAGE OF AN IMPORTANT GENE LOCUS FOR TUBEROUS SCLEROSIS TO A CHROMOSOME 16 MARKER FOR POLYCYSTIC KIDNEY-DISEASE
KANDT, RS
HAINES, JL
SMITH, M
NORTHRUP, H
GARDNER, RJM
SHORT, MP
DUMARS, K
ROACH, ES
STEINGOLD, S
WALL, S
BLANTON, SH
FLODMAN, P
KWIATKOWSKI, DJ
JEWELL, A
WEBER, JL
ROSES, AD
PERICAKVANCE, MA
[J]. NATURE GENETICS, 1992, 2 (01) : 37 - 41
[9] CONSTRUCTION OF A GT POLYMORPHISM MAP OF HUMAN 9Q
KWIATKOWSKI, DJ
HENSKE, EP
WEIMER, K
OZELIUS, L
GUSELLA, JF
HAINES, J
[J]. GENOMICS, 1992, 12 (02) : 229 - 240
[10] KWIATKOWSKI DJ, 1991, AM J HUM GENET, V49, P366

← 1 2 →