CAPILLARY ZONE ELECTROPHORESIS FOR THE RAPID SCREENING OF BANNED DRUGS IN SPORT

被引：21

作者：

GONZALEZ, E ^{[1
]}

LASERNA, JJ ^{[1
]}

机构：

[1] UNIV MALAGA,FAC SCI,DEPT ANALYT CHEM,E-29071 MALAGA,SPAIN

来源：

ELECTROPHORESIS | 1994年 / 15卷 / 02期

关键词：

D O I：

10.1002/elps.1150150141

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Capillary zone electrophoresis was used to analyze some drugs illegally used in sports. The spectroscopic characteristics and electrophoresis migration parameters of diuretics, narcotics-analgesics and beta-blockers were established. Analytical figures of merit including parameters on the precision of migration and limits of detection are discussed. Results for the separation of drugs of different doping families are discussed. An analysis of urine from a patient receiving daily dosis of atenolol is presented.

引用

页码：240 / 243

页数：4

共 15 条

[1] PHARMACEUTICAL ANALYSIS BY CAPILLARY ZONE ELECTROPHORESIS AND MICELLAR ELECTROKINETIC CAPILLARY CHROMATOGRAPHY [J].

ALTRIA, KD ;

SMITH, NW .

JOURNAL OF CHROMATOGRAPHY, 1991, 538 (02) :506-509

[2] ANALYSIS OF B6 VITAMERS BY MICELLAR ELECTROKINETIC CAPILLARY CHROMATOGRAPHY WITH LASER-EXCITED FLUORESCENCE DETECTION [J].

BURTON, DE ;

SEPANIAK, MJ ;

MASKARINEC, MP .

JOURNAL OF CHROMATOGRAPHIC SCIENCE, 1986, 24 (08) :347-351

[3]

EVENSON MA, 1992, CLIN CHEM, V38, P1847

[4] PULSED-LASER FLUORESCENCE DETECTION IN CAPILLARY ZONE ELECTROPHORESIS OF SOME BANNED SUBSTANCES IN SPORT [J].

GONZALEZ, E ;

MONTES, R ;

LASERNA, JJ .

ANALYTICA CHIMICA ACTA, 1993, 282 (03) :687-693

[5]

GOODMAN L, 1985, PHARMACOL BASIS THER, P1579

[6]

JORGENSON JW, 1986, ANAL CHEM, V58, P743

[7] NATIVE FLUORESCENCE DETECTION OF NUCLEIC-ACIDS AND DNA RESTRICTION FRAGMENTS IN CAPILLARY ELECTROPHORESIS [J].

MILOFSKY, RE ;

YEUNG, ES .

ANALYTICAL CHEMISTRY, 1993, 65 (02) :153-157

[8]

NAKAGAWA T, 1988, CHEM PHARM BULL, V36, P1622

[9]

NAKAGAWA T, 1989, CHEM PHARM BULL, V37, P707

[10] SEPARATION AND DETERMINATION OF ASPOXICILLIN IN HUMAN PLASMA BY MICELLAR ELECTROKINETIC CHROMATOGRAPHY WITH DIRECT SAMPLE INJECTION [J].

NISHI, H ;

FUKUYAMA, T ;

MATSUO, M .

JOURNAL OF CHROMATOGRAPHY, 1990, 515 :245-255

← 1 2 →