THE CHIRAL TOTAL SYNTHESIS OF (-)-ONCINOTINE

被引：14

作者：

INA, H ^{[1
]}

ITO, M ^{[1
]}

KIBAYASHI, C ^{[1
]}

机构：

[1] TOKYO UNIV PHARM & LIFE SCI,HACHIOJI,TOKYO 19203,JAPAN

来源：

JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS | 1995年 / 10期

关键词：

D O I：

10.1039/c39950001015

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The first chiral synthesis of (-)-oncinotine 1 in natural form has been achieved starting from the protected (S)-N-benzyloxycarbonyl-2-piperidylacetaldehyde 3 based on a new route involving 17-membered ring formation via iminium cyclization, which establishes the 17R absolute configuration of natural 1.

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页码：1015 / 1016

页数：2

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