OLIGOPEPTIDE FRAGMENTATION VIEWED AS CONSTANT NEUTRAL LOSS

被引:4
作者
FENSELAU, C [1 ]
MURPHY, CM [1 ]
COTTER, RJ [1 ]
机构
[1] JOHNS HOPKINS UNIV,DEPT PHARMACOL & MOLEC SCI,BALTIMORE,MD 21218
关键词
D O I
10.1016/1044-0305(90)85010-J
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
Spectra were recorded of all fragment ions formed by elimination of 28-u neutral fragments in fast atom bombardment spectra of peptides in the mass range 1000-1800 u, This approach can provide less complex spectra than either conventionally scanned spectra or product ion scans from collisionaIly activated four-sector experiments, and spectra that contain information that is both overlapping and complementary to those from the other techniques. Constant neutral loss spectra may provide a reading frame for distinguishing sequence ion series in tandem or single analyzer spectra. © 1990 American Society for Mass Spectrometry.
引用
收藏
页码:336 / 340
页数:5
相关论文
共 12 条
[11]   ENDOTHERMIC ION MOLECULE REACTIONS .2. REACTIONS BETWEEN PEPTIDES WITH AND WITHOUT BASIC RESIDUES AND AMMONIA [J].
ORLANDO, R ;
FENSELAU, C ;
COTTER, RJ .
ORGANIC MASS SPECTROMETRY, 1989, 24 (11) :1033-1042
[12]  
ZACKETT D, 1979, J AM CHEM SOC, V101, P6781