HIGHLY REGIOSELECTIVE MONOALKYLATION OF KETONES VIA MANGANESE ENOLATES PREPARED FROM LITHIUM ENOLATES

被引：19

作者：

CAHIEZ, G

CHAU, K

CLERY, P

机构：

[1] Laboratoire de Chimie des Organoéléments, associé au CNRS Université P. et M. Curie, F-75252 Paris Cédex 05

来源：

TETRAHEDRON LETTERS | 1994年 / 35卷 / 19期

关键词：

D O I：

10.1016/S0040-4039(00)76830-4

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Li-enolates are readily converted to Mn-enolates by treatment with manganese halides. In THF, the reaction is easily and economically performed with manganese chloride at room temperature. Mn-enolates can then be regioselectively monoalkylated in good yields. The formation of di and polyalkylated products is never observed (< 1%).

引用

页码：3069 / 3072

页数：4

共 14 条

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